BOTOX® Cosmetic A simple, nonsurgical, physician-administered treatment that can temporarily smooth moderate to severe frown lines between the brows in people from 18 to 65 years of age. It is the only treatment of its type approved by the Food and Drug Administration (FDA). Radiesse® Wrinkle Filler The unique formulation stimulates collagenesis – the production of new collagen – which results in increased volume for natural looking wrinkle correction that may last a year or more in many patients The RADIESSE wrinkle filler difference: Stimulates the body's own natural collagen production Instantly corrects wrinkles Results that may last a year or more in many patients Now FDA approved to enhance patient comfort with lidocaine mixing